Im having this same issue in my 08 v6 4wd, my on board says I am averaging 15.4 mpg. Im at 225,000 miles. I just bought the vehicle from a friends family member, which are mainly highway miles, about a year ago. When I first bought it, the onboard said 27 mpg! I was so happy. Im not sure how long the truck sat for, but the battery was not dead when I originally checked it out. The rapid decline in mpg made me do the plugs, (ngk) maf cleaning, dfpe egr pressure feedback sensor (motorcraft, I had a cel for that), fuel injection pressure sensor, (motorcraft) and im still looking at terrible mileage. Im going to change both upstream o2 sensors, but I doubt ill see a response. Since I got the code for the dfpe egr sensor, I was thinking maybe my egr valve is on its way out, but I dont have any issue with drivability except the car feels like it has no power. I figure its just a slow suv, its always been slow. doesn't feel like its choking or anything, just feels like 150hp in an suv. Good luck