2020 Ttanium Hybrid/2009 Limited Hybrid/1978 F-250 Custom
Just looking at them, no.
The front seats are not 60/40 split, so these floor mats would not work. Willing to bet the cut out for the center console is also too small, it is definitely not in the right place.
I installed a seat cover set, and I cannot find a way to release the sliding seat bottom, to fold up like in my 2009