I don't know about the engine block and mounts, but I do know that the PCM and a good chunk of the wiring harness is different for the 3.0L V6.
I can give you wiring diagrams if you decide to upgrade to the 3.0, but you'll probably need a lot of new parts.
Also (and this is important), don't buy parts from a 2001-2004 Escape if you buy this 2005 Escape. Ford changed a large number of parts of the front end of the 2005-2007 models, even though they look the same as the 2001-2004 models. This includes engine mounts, suspension parts, and much of the front structure.
I can give you wiring diagrams if you decide to upgrade to the 3.0, but you'll probably need a lot of new parts.
Also (and this is important), don't buy parts from a 2001-2004 Escape if you buy this 2005 Escape. Ford changed a large number of parts of the front end of the 2005-2007 models, even though they look the same as the 2001-2004 models. This includes engine mounts, suspension parts, and much of the front structure.