The auction site indicates 235/50zr18 tires, which would be smaller over all diameter/circumference. Even with 255/50zr18, it is still a smaller diameter tire than the stock Escape, but a little closer, and might work out alright.
Yes! 18" rims will fit your suv without any issue and don't worry about the lug pattern because it's universal. As long as the rim is not specifically designed for a luxury car (BMW, Lotus, Benz) they will bolt right on. How about 22" on that baby. I have 20" on mine currently, and I considering upgrading to 22".